About 30 results found for searched term "P2 Receptor" (0.105 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1909 | GW 791343 dihydrochloride | P2 Receptor |
| GW 791343 dihydrochloride is a non-competitive inhibitor of human P2X(7) receptor. | ||
| M2234 | Prasugrel | P2 Receptor |
| Effient, Efient | ||
| Prasugrel is a platelet inhibitor irreversibly binding to P2Y12 receptors. | ||
| M2256 | Ivermectin (MK-933) | Autophagy |
| Stromectol; MK-933 | ||
| Ivermectin (MK-933) is a positive allosteric modulator of the α7 neuronal nicotinic acetylcholine receptor and the purinergic P2X4 receptor. Importin α5 inhibitor ivermectin effectively abrogates STAT1-importin α5 interactions. | ||
| M2418 | AZD1981 | GPR/FFAR |
| AZD1981 is a potent, selective CRTh2 (DP2) receptor antagonist with IC50 of 4 nM, showing >1000-fold selectivity over more than 340 other enzymes and receptors, including DP1. | ||
| M2428 | BAF312 | S1P Receptor |
| Siponimod | ||
| BAF312 (Siponimod) is a next-generation S1P receptor modulator, selective for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, exhibits >1000-fold selectivity over S1P2, S1P3 and S1P4 receptors. | ||
| M2869 | MRS 2578 | P2 Receptor |
| MRS2578 is a potent P2Y6 receptor antagonist with IC50 of 37 nM, exhibits insignificant activity at P2Y1, P2Y2, P2Y4,and P2Y11 receptors. | ||
| M2954 | PPADS Tetrasodium Salt | P2 Receptor |
| PPADS tetrasodium salt is a non-selective P2 purinergic antagonist blocking recombinant P2X1, P2X2, P2X3, P2X5 with IC50 of 1-2.6 μM, native P2Y2-like with IC50 of ~ 0.9 mM, and recombinant P2Y4 receptors with IC50 of ~ 15 mM | ||
| M3069 | Ticagrelor | P2 Receptor |
| AR-C 126532XX; AZD6140 | ||
| Ticagrelor is the first reversibly binding oral P2Y12 receptor antagonist with Ki of 2 nM respectively. | ||
| M3185 | Ticlopidine hydrochloride | P2 Receptor |
| Ticlopidine hydrochloride is a selective P2Y12 receptor antagonist. | ||
| M3949 | AF 353 | P2 Receptor |
| Ro-4 | ||
| AF-353 is a novel, potent and orally bioavailable P2X3 receptor antagonist, with a pIC50 of 8.0 for both human and rat P2X3, and with a pIC50 of 7.3 for human P2X2/3. | ||
| M5023 | Clopidogrel hydrogen sulfate | P2 Receptor |
| (S)-(+)-Clopidogrel bisulfate; (S)-(+)-Clopidogrel hydrogen sulfate | ||
| S-(+)-Clopidogrel Hydrogen Sulfate is the S enantiomer of clopidogrel and a P2Y12 receptor inhibitor. | ||
| M6279 | Laropiprant | Dopamine Receptor |
| MK-0524 | ||
| Laropiprant is a potent, selective DP1 receptor antagonist with Ki value of 0.57 nM, and exhibits > 1,000 fold selectivity over DP2 receptor (Ki=0.75 μM). | ||
| M6347 | 5-BDBD | P2 Receptor |
| 5BDBD | ||
| 5-BDBD is a potent P2X4 receptor antagonist. | ||
| M6457 | AR-C 118925XX | Others |
| AR-C 118925XX is a selective, competitive P2Y 2 receptor antagonist. | ||
| M6475 | AZ 10606120 dihydrochloride | P2 Receptor |
| AZ 10606120 dihydrochloride is a potent P2X 7 receptor antagonist. | ||
| M6876 | L-161982 | Prostaglandin Receptor |
| L161982 | ||
| L-161982 is a EP4 receptor antagonist that is selective over all other members of the prostanoid receptor family (Ki values are 0.024, 0.71, 1.90, 5.10, 5.63, 6.74, 19 and 23 μM for human EP4, TP, EP3, DP, FP, IP, EP1 and EP2 receptors respectively). L-161982 completely blocks PGE2-induced ERK phosphorylation and cell proliferation of HCA-7 cells. | ||
| M7167 | PSB-0739 | P2 Receptor |
| PSB 0739 | ||
| PSB 0739 is a highly potent P2Y12 receptor antagonist with a Ki values of 24.9 nM. | ||
| M7452 | UDP disodium salt | P2 Receptor |
| UDP disodium salt is a endogenous ligand; competitive antagonist at P2Y 14 receptors. | ||
| M7668 | BMS-646786 | P2 Receptor |
| BPTU | ||
| BMS-646786 is a potent and specific inhibitor of P2Y1 purinergic receptor that inhibits ADP-mediated platelet aggregation in human blood samples. | ||
| M7673 | BMS-870145 | Others |
| BMS-870145 is an orally available, potent and selective P2Y1 purinergic receptor antagonist. | ||
| M7932 | MRS 2395 | Others |
| Antagonist for P2Y12 purinoceptor; inhibits ADP-induced aggregation in rat platelets and antagonizes ADP-induced inhibition of cAMP in rat and human platelets in the presence of PGE1 without affecting P2Y1 receptor-induced PLC activity in transfected astrocytoma cells. | ||
| M8120 | PF-04217329 | Others |
| PF-04217329 is a selective and potent prostaglandin EP2 receptor agonist. | ||
| M9182 | Gefapixant | P2 Receptor |
| AF-219; MK-7264 | ||
| Gefapixant, also known as AF-219 or MK-7264, is a P2X3 receptor antagonist. | ||
| M9232 | PF-04418948 | Prostaglandin Receptor |
| PF-04418948 is a novel, potent and selective prostaglandin EP2 receptor antagonist with IC50 of 16 nM. | ||
| M9854 | Taprenepag | Prostaglandin Receptor |
| CP-544326 | ||
| Taprenepag (CP-544326) is a potent selective prostagenin EP(2) agonist with IC50 of 10 and 15 nM for human and rat EP2, respectively. Taprenepag has higher selectivity for EP2 than other EP receptors (IC50>3200 nM for EP1, EP3 and EP4) and a group of 37 G-protein-coupled receptors. | ||
| M9983 | Recombinant Human IL-36RA Protein (HEK293, C-His) | Recombinant Proteins |
| Interleukin-36RA; IL-1F5 | ||
| Recombinant Human IL-36RA Protein (originally named IL-1F5) can antagonize IL-36α, β or γ-induced NF-RrpB signaling by binding to IL-1Rrp2 receptor, thereby preventing the initiation of functional signals. | ||
| M10064 | Uridine 5'-diphosphoglucose disodium salt | Others |
| UDP-Glc | ||
| Uridine 5'-diphosphoglucose disodium salt is an agonist of the P2Y14 receptor. | ||
| M10442 | Minodronic acid | P2 Receptor |
| YM-529; ONO-5920; YH-529 | ||
| Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors, Minodronic acid (YM-529) is also a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis, and inhibits metastasis of various types of cancer cells. | ||
| M10481 | Omidenepag | Prostaglandin Receptor |
| OMD | ||
| Omidenepag,a pharmacologically active form of Omidenepag Isopropyl, is a selective, non-prostanoid EP2 receptor agonist, with an EC50 of 1.1 nM. | ||
| M10679 | Evatanepag | Prostaglandin Receptor |
| CP-533536 free acid | ||
| Evatanepag (CP-533536 free acid) is a potent selective EP2 receptor agonist with an IC50 of 50 nM for rEP2. | ||
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